49ers vs Rams Player Prop Predictions - NFL Week 5 - TNF
49ers vs Rams player props predictions for Thursday. Passing, receiving, and rushing stat lines plus the best 49ers vs Rams prop picks.

49ers vs Rams Player Props Predictions
The San Francisco 49ers travel south to face the Los Angeles Rams in an NFC West rivalry game for Thursday Night Football on October 2nd at 8:30 pm EST. With Brock Purdy leading San Francisco and Matthew Stafford guiding the Rams, this matchup is loaded with intriguing 49ers vs Rams player props. QuickPicks is the perfect way to put your football IQ to the test in head-to-head stat line contests.
Looking for more ways to play this week? Don’t miss our Week 5 NFL Survivor picks and Week 5 NFL Pick’em breakdown for deeper strategy.
Passing Yards Props for 49ers vs Rams
Brock Purdy — 240.5 Pass Yards — Less
Purdy has been efficient, but San Francisco often leans on balance with McCaffrey and the ground game. Against LA’s defense, “Less” feels right.
Matthew Stafford — 235.5 Pass Yards — More
Stafford thrives in primetime and isn’t afraid to attack through the air. Expect him to clear this number at home.

Receiving Yards Player Props for 49ers vs Rams
Puka Nacua — 98.5 Rec Yards — More
Nacua has been a target machine and Stafford’s go-to weapon. In a divisional spotlight, “More” is the lean.

Rushing Yards Props for 49ers vs Rams
Kyren Williams — 68.5 Rush Yards — Less
Williams is solid but could struggle against San Francisco’s front seven. Lean “Less” on his rushing line.
Christian McCaffrey — 60.5 Rush Yards — More
McCaffrey remains the engine of the 49ers’ offense. Expect him to get volume carries and surpass this number.

Why QuickPicks for 49ers vs Rams Player Props
QuickPicks makes contests like 49ers vs Rams player props more fun by testing your skill and football knowledge. On top of that, QuickPicks provides unmatched multipliers compared to the competition. The payout chart shows that QuickPicks outpaces both Underdog and PrizePicks for 4, 5, and 6-pick entries, giving you better value when you’re confident in your picks. QuickPicks also pits player against player, which means someone always wins — unlike PrizePicks or Underdog.
Invite your friends, build your picks, and put your football insights to the test.

49ers vs Rams Player Prop Conclusion for Thursday Night Football
From Stafford’s passing volume to McCaffrey’s rushing production, Thursday Night Football delivers plenty of opportunities for sharp 49ers vs Rams prop picks. Build your QuickPicks entries, challenge your friends, and enjoy a divisional battle that should deliver fireworks.
This article contains betting tips and strategies for basketball fans. Splash Sports’ basketball fantasy contests are NOT sports betting. If you want to place bets on basketball or other sports, there are plenty of other sites to choose from.
While this article contains general betting tips and strategies for sports fans, please note that Splash Sports does not offer sports betting of any kind. Splash Sports offers fantasy contests and other games of skill where you can organize contests and compete with your friends for real money or play against the community for cash prizes.
This article contains betting tips and strategies for golf fans. Splash Sports’ golf fantasy contests are NOT sports betting. If you want to place bets on golf or other sports, there are plenty of other sites to choose from.
While this article contains general betting tips and strategies for sports fans, please note that Splash Sports does not offer sports betting of any kind. Splash Sports offers fantasy contests and other games of skill where you can organize contests and compete with your friends for real money or play against the community for cash prizes.
This article contains betting tips and strategies for football fans. Splash Sports’ football fantasy contests are NOT sports betting. If you want to place bets on football or other sports, there are plenty of other sites to choose from.
While this article contains general betting tips and strategies for sports fans, please note that Splash Sports does not offer sports betting of any kind. Splash Sports offers fantasy contests and other games of skill where you can organize contests and compete with your friends for real money or play against the community for cash prizes.
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