NFL Week 4 Pick’em 2025: Contests, Picks, and More

Week 4 of the 2025 NFL season brings a mix of international action, division rivalries, and heavyweight showdowns. Many fans are searching for “NFL week 4 pick’em sheets” to track their selections—but paper pick’em sheets are outdated. Splash Sports delivers a smarter, skill-based alternative where scoring is automated, entries are mobile-friendly, and contest prizes are guaranteed.

Below, you’ll find our straight-up Week 4 NFL pick’em predictions for every game on the slate.

Top NFL Pick’em Week 4 Contests to Enter

Splash $15K NFL Pick All ATS – Week 4 – A $10 entry contest with $15,003 in guaranteed contest prizes. Players make ATS picks for every game, with payouts going to the top 73 finishers. The top three take home $1,905.83, $1,500.30, and $1,125.22.

Splash $5K NFL Pick All ATS – Week 4 – A $25 entry contest with $5,017.50 in guaranteed contest prizes. Players pick every game against the spread, with payouts to the top 25 entries. First place wins $1,003.56, second $752.62, and third $602.10.

Sloprules NFL Pick’em Confidence – Week 4 – A $20 entry contest with $5,004 in guaranteed contest prizes. Players assign confidence points to each game, with payouts to the top 25 finishers. First place wins $1,000.80, second $750.60, and third $600.48.

NFL Pick’em Week 4 Predictions & Strategy

Here’s the official Week 4 slate, with spreads from DraftKings. Use these Safe Picks and ATS leans to guide your entries.

Seahawks vs. Cardinals (TNF)

• Safe Pick (Winner): Cardinals – Home-field advantage helps Arizona edge Seattle.
  
  
• Against the Spread (ATS): Cardinals -2.5

Vikings vs. Steelers (Dublin, Ireland)

• Safe Pick (Winner): Steelers – Pittsburgh’s defense controls the tempo overseas.
  
  
• Against the Spread (ATS): Steelers -2.5

Commanders vs. Falcons

• Safe Pick (Winner): Commanders – Washington’s defense holds up on the road.
  
  
• Against the Spread (ATS): Commanders -1.5

Saints vs. Bills

• Safe Pick (Winner): Bills – Buffalo dominates at home.
  
  
• Against the Spread (ATS): Bills -14.5

Browns vs. Lions

• Safe Pick (Winner): Lions – Detroit’s physicality makes the difference.
  
  
• Against the Spread (ATS): Lions -9.5

Titans vs. Texans

• Safe Pick (Winner): Texans – Houston’s young stars shine at home.
  
  
• Against the Spread (ATS): Texans -6.5

Panthers vs. Patriots

• Safe Pick (Winner): Patriots – New England defense secures a home win.
  
  
• Against the Spread (ATS): Patriots -5.5

Chargers vs. Giants

• Safe Pick (Winner): Chargers – Offensive firepower too much for New York.
  
  
• Against the Spread (ATS): Chargers -5.5

Eagles vs. Buccaneers

• Safe Pick (Winner): Eagles – Balanced roster carries them to a road win.
  
  
• Against the Spread (ATS): Eagles -2.5

Colts vs. Rams

• Safe Pick (Winner): Rams – Los Angeles defends SoFi against Indy.
  
  
• Against the Spread (ATS): Rams -4.5

Jaguars vs. 49ers

• Safe Pick (Winner): 49ers – San Francisco overwhelms Jacksonville.
  
  
• Against the Spread (ATS): 49ers -3

Ravens vs. Chiefs

• Safe Pick (Winner): Ravens – Baltimore’s defense delivers a statement road win.
  
  
• Against the Spread (ATS): Ravens -2.5

Bears vs. Raiders

• Safe Pick (Winner): Raiders – Las Vegas protects home field.
  
  
• Against the Spread (ATS): Raiders -1.5

Packers vs. Cowboys (SNF)

• Safe Pick (Winner): Packers – Green Bay finds enough balance to steal one.
  
  
• Against the Spread (ATS): Packers -4.5

Jets vs. Dolphins (MNF Game 1)

• Safe Pick (Winner): Dolphins – Miami’s speed wins at home.
  
  
• Against the Spread (ATS): Dolphins -2.5

Bengals vs. Broncos (MNF Game 2)

• Safe Pick (Winner): Broncos – Denver defends Mile High under the lights.
  
  
• Against the Spread (ATS): Broncos -6.5

Tips for NFL Pick’em Week 4

1. Don’t chase every upset. In Pick All contests, locking in safer winners usually outpaces contrarian swings.
   
   
2. ATS calls reward matchup knowledge. Look for trench mismatches and QB play.
   
   
3. Confidence rankings matter. Place your highest confidence points on teams with clear moneyline edges (Bills, 49ers).

Why NFL Pick’em Contests Beat Pick’em Sheets

Fans may still search for “NFL week 4 pick’em sheets,” but Splash Sports provides the modern solution. Instead of tracking games manually, Splash delivers:

• Automated scoring so you never need to calculate results.
  
  
• Mobile play for easy access on game day.
  
  
• Contest prizes guaranteed for winners.
  
  
• Play against friends, not the house.

It’s like your old pick’em sheet—but smarter, faster, and built for today’s NFL fan.

Conclusion

NFL Week 4 features everything from international action in Dublin to a Sunday night classic in Dallas. Whether you’re entering Pick All or Confidence contests, Splash Sports is the top destination to put your NFL knowledge and skill to the test.

👉 Ready to play? Check out the live NFL pick’em contests on Splash Sports and start building your winning sheet today.